Cancer of the lymph nodes, such as Hodgkin’s Disease or Non-Hodgkin’s Lymphoma, can often involve multiple lymph node regions and occasionally other (extra nodal) sites. Optimal treatment often involves chemotherapy, and radiation therapy is frequently used to treat involved or bulky sites, often using large fields of treatment to cover multiple lymph node bearing regions. Although the effective doses are low and can usually be given in 3-4 weeks, sometimes large volumes of lung or small intestine can be at risk for damage. Tomotherapy can do a good job of limiting dosage to these normal structures, and by using CT image guidance, the uncertainty of reproducing treatment positioning for large fields of treatment can be reduced.